Circulatory changes produced by the Valsalva maneuver in normal subjects, patients with mitral stenosis, and autonomic nervous system alterations.

نویسندگان

  • H D McINTOSH
  • J F BURNUM
  • J B HICKAM
  • J V WARREN
چکیده

The cardiac output has been measured during the immediate post-Valsalva maneuver recovery period in normal subjects, patients with clinically significant mitral stenosis, and patients with alterations of the autonomic nervous system. When compared with the resting value, it was found that normal subjects had a decrease in cardiac output during the immediate post-Valsalva recovery period, while patients with mitral stenosis had an increased output following the same stress. Three patients with alterations of the autonomic nervous system had a variable response. Changes in total peripheral vascular resistance usually were directionally opposite to changes in the cardiac output. The difficulties of attaching clinical significance to a patient's response to the Valsalva maneuver are considered. R ECENT reports suggest that patients with cardiovascular abnormalities, especially mitral stenosis, may respond differently, when compared with normal subjects , to the stress of a Valsalva maneuver1-4 (a forced expiration with a closed glottis, after a full inspiration). It has been reported that the absence of bradycardia following the Valsalva maneuver may serve as an index for the degree of mitral stenosis.' It has also been observed that, unlike normal subjects, patients with mitral stenosis can maintain their systolic blood pressure equal to the resting level during the forced expiratory phase of the Valsalva maneuver when performed under effective autonomic blockade.4 511 maneuver have been adequately reviewedS'7; however, few actual measurements of the cardiac output and peripheral resistance during and following this maneuver have been reported. Such measurements were made in this study in normal subjects, patients with mitral stenosis, and patients with alterations of the autonomic nervous system.

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عنوان ژورنال:
  • Circulation

دوره 9 4  شماره 

صفحات  -

تاریخ انتشار 1954